Recombinant Mouse Bbc3 Protein, Myc/DDK-tagged

• Cat.No.: Bbc3-1827M
• Product Overview: Purified recombinant protein of mouse full-length BCL2 binding component 3 (Bbc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
• Molecular Mass: 21.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Bbc3 BCL2 binding component 3 [ Mus musculus (house mouse) ]
• Official Symbol: Bbc3
• Synonyms: BBC3; BCL2 binding component 3; bcl-2-binding component 3; BH3-only; Bcl-2 binding component 3; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1
• Gene ID: 170770
• mRNA Refseq: NM_133234
• Protein Refseq: NP_573497
• UniProt ID: Q99ML1