Recombinant Mouse Bmp2 protein, His-tagged
| Cat.No. : | Bmp2-562M |
| Product Overview : | Recombinant Mouse Bmp2 (P21274) aa. (Gln281~Arg394) fused with N-terminal His tag was produced in E. coli cells. |
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| Species : | Mouse |
| Source : | E.coli |
| Tag : | His |
| Protein Length : | Gln281~Arg394 |
| Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. While a homozygous knockout mouse for this gene exhibits embryonic lethality, conditional knockout mice have defects in bone, cartilage and heart development. |
| Form : | Freeze-dried powder |
| Molecular Mass : | 15kDa as determined by SDS-PAGE reducing conditions |
| Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
| Purity : | > 97% |
| Characteristic : | The isoelectric point is 8.2. |
| Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
| Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Concentration : | 200µg/mL |
| Storage buffer : | 10mM PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300. |
| Reconstitution : | Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex |
| Gene Name | Bmp2 bone morphogenetic protein 2 [ Mus musculus (house mouse) ] |
| Official Symbol | Bmp2 |
| Synonyms | Bmp2; bone morphogenetic protein 2; Bmp2a; AI467020; bone morphogenetic protein 2A |
| Gene ID | 12156 |
| mRNA Refseq | NM_007553.3 |
| Protein Refseq | NP_031579.2 |
| UniProt ID | P21274 |
Not For Human Consumption!
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