Recombinant Mouse CHRDL1 Protein (23-447 aa), His-Myc-tagged

• Cat.No.: CHRDL1-2749M
• Product Overview: Recombinant Mouse CHRDL1 Protein (23-447 aa) is produced by Baculovirus expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Neuroscience. Protein Description: Full Length of Mature Protein.

Specification

• Description: Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the inducing activity of BMP2. Plays a role during anterior segment eye development.
• Source: Baculovirus
• Species: Mouse
• Tag: His-Myc
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 52.2 kDa
• Protein length: 23-447 aa
• AA Sequence: EQVKHSDTYCVFQDKKYRVGEKWHP YLEPYGLVYCVNCICSENGNVLCSR VRCPSLHCLSPVHIPHLCCPRCPDS LPPVNNKVTSKSCEYNGTTYQHGEL FIAEGLFQNRQPNQCSQCSCSEGNV YCGLKTCPKLTCAFPVSVPDSCCRV CRGDAELSWEHADGDIFRQPANREA RHSYLRSPYDPPPNRQAGGLPRFPG SRSHRGAVIDSQQASGTIVQIVINN KHKHGQVCVSNGKTYSHGESWHPNL RAFGIVECVLCTCNVTKQECKKIHC PNRYPCKYPQKIDGKCCKVCPEEPP SQNFDSKGSFCGEETMPVYESVFME DGETTRKVALETERPPQVEVHVWTI QKGILQHFHIEKISKRMFGELHHFK LVTRTTLNQWKLFTEGEAQLSQMCS SQVCRTELEDLVQVLYLGRPEKDHC
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: Chrdl1 chordin-like 1 [ Mus musculus ]
• Official Symbol: CHRDL1
• Synonyms: CHRDL1; chordin-like 1; neuralin-1; neurogenesin-1; ventroptin-beta; ventroptin-alpha; CHL; CHL1; VOPT; Nrln1
• Gene ID: 83453
• mRNA Refseq: NM_001114385
• Protein Refseq: NP_001107857
• UniProt ID: Q920C1