Recombinant Mouse Chrna6 Protein, His&GST-tagged

• Cat.No.: Chrna6-780M
• Product Overview: Recombinant Mouse Chrna6 Protein (Cys31-Pro240) with His&GST tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: GST&His
• Protein Length: Cys31-Pro240
• Description: Enables acetylcholine-gated cation-selective channel activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within membrane depolarization and regulation of dopamine secretion. Located in dopaminergic synapse. Part of acetylcholine-gated channel complex. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Is expressed in central nervous system and retina. Orthologous to human CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 54.9 kDa; Accurate Molecular Mass: 55 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 [ Mus musculus (house mouse) ]
• Official Symbol: Chrna6
• Synonyms: CHRNA6; cholinergic receptor, nicotinic, alpha polypeptide 6; neuronal acetylcholine receptor subunit alpha-6; alpha6 nAChR; acetylcholine receptor alpha 6 neural; nicotinic acetylcholine receptor subunit alpha 6; Acra6; Nica6
• Gene ID: 11440
• mRNA Refseq: NM_021369
• Protein Refseq: NP_067344
• UniProt ID: Q9R0W9