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Recombinant Mouse Cth Protein, MYC/DDK-tagged

Cat.No. : Cth-350M
Product Overview : Purified recombinant protein of full-length mouse cystathionase (cystathionine gamma-lyase) (Cth), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 43.6 kDa
Purity : >80%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cth cystathionase (cystathionine gamma-lyase) [ Mus musculus (house mouse) ]
Official Symbol : Cth
Synonyms : Cth; cystathionase (cystathionine gamma-lyase); CSE; Cys3; AI314617; BC019483; 0610010I13Rik; cystathionine gamma-lyase; cysteine-protein sulfhydrase; EC 4.4.1.1
Gene ID : 107869
mRNA Refseq : NM_145953
Protein Refseq : NP_666065
UniProt ID : Q8VCN5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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