Recombinant Mouse Cyp17a1 Protein, Myc/DDK-tagged

• Cat.No.: Cyp17a1-2410M
• Product Overview: Purified recombinant protein of mouse full-length cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
• Molecular Mass: 57.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 [ Mus musculus (house mouse) ]
• Official Symbol: Cyp17a1
• Synonyms: CYP17A1; cytochrome P450, family 17, subfamily a, polypeptide 1; steroid 17-alpha-hydroxylase/17,20 lyase; CYPXVII; cytochrome P450c17; cytochrome P450, 17; cytochrome P450-C17; cytochrome P450 17A1; cytochrome P450, 17a1; steroid 17-alpha hydroxylase; Cyp17; p450c17
• Gene ID: 13074
• mRNA Refseq: NM_007809
• Protein Refseq: NP_031835
• UniProt ID: P27786