Recombinant Mouse Dnajb2 Protein, Myc/DDK-tagged

• Cat.No.: Dnajb2-2598M
• Product Overview: Purified recombinant protein of mouse full-length DnaJ heat shock protein family (Hsp40) member B2 (Dnajb2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functions as a co-chaperone, regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family. In parallel, also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins. Thereby, may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT, MC4R, PRKN, RHO and SOD1 and be crucial for many biological processes. Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 30.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 [ Mus musculus (house mouse) ]
• Official Symbol: Dnajb2
• Synonyms: DNAJB2; DnaJ (Hsp40) homolog, subfamily B, member 2; dnaJ homolog subfamily B member 2; heat shock protein, DNAJ-like 1; dnaJ homolog subfamily B member 10; DnaJ (Hsp40) homolog, subfamily B, member 10; Hsj1; mDj8; Dnajb10; 2700059H22Rik; MGC113758
• Gene ID: 56812
• mRNA Refseq: NM_001159885
• Protein Refseq: NP_001153357
• UniProt ID: Q9QYI5