Recombinant Mouse Dsc3 Protein, His-tagged

• Cat.No.: Dsc3-1385M
• Product Overview: Recombinant Mouse Dsc3 Protein (Arg136-Phe355) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the cadherin family of proteins that mediates adhesion in desmosomes. Together with desmogleins, the encoded protein forms the transmembrane core of desmosomes, a multiprotein complex involved in cell adhesion, organization of the cytoskeleton, cell sorting and cell signaling. Mice lacking the encoded protein exhibit a pre-implantation lethal phenotype. This gene is located in a cluster of desmosomal cadherin genes on chromosome 18. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein.
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.4 kDa
  Accurate Molecular Mass: 32 kDa
• Protein length: Arg136-Phe355
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Dsc3 desmocollin 3 [ Mus musculus (house mouse) ]
• Official Symbol: Dsc3
• Synonyms: DSC3; desmocollin 3; desmocollin-3; 5430426I24Rik
• Gene ID: 13507
• mRNA Refseq: NM_007882
• Protein Refseq: NP_031908
• UniProt ID: P55850