| Cat.No.: | EFEMP1-2166M |
| Product Overview: | Recombinant Mouse EFEMP1 Protein (18-493 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein. |
| Description: | Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. |
| Source: | Yeast |
| Species: | Mouse |
| Tag : | His |
| Form: | Tris-based buffer,50% glycerol |
| Molecular Mass: | 55.0 kDa |
| Protein length: | 18-493 aa |
| AA Sequence: | QYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF |
| Purity: | > 90% as determined by SDS-PAGE. |
| Notes: | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration: | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Gene Name: | Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 [ Mus musculus ] |
| Official Symbol: | EFEMP1 |
| Synonyms: | EFEMP1; FIBL-3; fibulin-3; MGC37612; |
| Gene ID: | 216616 |
| mRNA Refseq: | NM_146015 |
| Protein Refseq: | NP_666127 |
| UniProt ID: | Q8BPB5 |
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