Recombinant Mouse EFEMP1 Protein (18-493 aa), His-tagged

• Cat.No.: EFEMP1-2166M
• Product Overview: Recombinant Mouse EFEMP1 Protein (18-493 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein.

Specification

• Description: Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
• Source: Yeast
• Species: Mouse
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 55.0 kDa
• Protein length: 18-493 aa
• AA Sequence: QYTEETITYTQCTDGYEWDPIRQQC KDIDECDIVPDACKGGMKCVNHYGG YLCLPKTAQIIVNNEHPQQETPAAE ASSGATTGTVAARSMATSGVVPGGG FMASATAVAGPEVQTGRNNFVIRRN PADPQRIPSNPSHRIQCAAGYEQSE HNVCQDIDECTSGTHNCRTDQVCIN LRGSFTCQCLPGYQKRGEQCVDIDE CTVPPYCHQRCVNTPGSFYCQCSPG FQLAANNYTCVDINECDASNQCAQQ CYNILGSFICQCNQGYELSSDRLNC EDIDECRTSSYLCQYQCVNEPGKFS CMCPQGYEVVRSRTCQDINECETTN ECREDEMCWNYHGGFRCYPRNPCQD HYVLTSENRCVCPVSNTMCRELPQS IVYKYMSIRSDRSVPSDIFQIQATM IYANTINTFRIKSGNENGEFYLRQT SPVSAMLVLVKSLSGPREYIVDLEM LTVSSIGTFRTSSVLRLTIIVGPFS F
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 [ Mus musculus ]
• Official Symbol: EFEMP1
• Synonyms: EFEMP1; FIBL-3; fibulin-3; MGC37612
• Gene ID: 216616
• mRNA Refseq: NM_146015
• Protein Refseq: NP_666127
• UniProt ID: Q8BPB5