Recombinant Mouse ENPP2 protein(Ser49-Ile862), His-tagged

• Cat.No.: Enpp2-1189M
• Product Overview: Recombinant Mouse ENPP2 (Q9R1E6-1) (Ser 49-Ile 862) was expressed in HEK293, fused with a polyhistidine tag at the N-terminus.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His
• Protein length: Ser49-Ile862
• Form: Lyophilized from sterile 20mM Tris, 150mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant mouse ENPP2 comprises 833 amino acids and predicts a molecular mass of 96 kDa. As a result of glycosylation, the apparent molecular mass of mouse ENPP2 is approximately 55-75 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 93 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 [ Mus musculus ]
• Official Symbol: ENPP2
• Synonyms: ENPP2; ectonucleotide pyrophosphatase/phosphodiesterase 2; ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; lysoPLD; autotaxin; extracellular lysophospholipase D; phosphodiesterase I/nucleotide pyrophosphatase 2; ATX; Npps2; Pdnp2; PD-Ialpha
• Gene ID: 18606
• mRNA Refseq: NM_001136077
• Protein Refseq: NP_001129549

Reviews

02/21/2023

Excellent after-sales service, solving many experimental problems.

11/09/2022

Fast and timely shipment helped me to get satisfactory experimental results in short time.

04/01/2022

Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

Q&As

What effects does overexpression of ENPP2 have on HUVEC cells?

Overexpression of ENPP2 promotes proliferation and migration of HUVEC cells.

What biological processes is ENPP2 involved in?

ENPP2 is involved in a variety of physiological processes such as angiogenesis, inflammatory response, and neurodevelopment.

What does ENPP2 have to do with lysophosphatidic acid?

ENPP2 can secrete lysophosphatidic acid.

What parts of the structural domain make up ENPP2?

ENPP2 consists of two N-terminal growth hormone B-like structural domains, a central catalytic phosphodiesterase structural domain and a C-terminal nuclease-like structural domain.

In which organs is ENPP2 expressed?

ENPP2 is expressed in the brain, placenta and ovary.