Recombinant Mouse Fam107a Protein, Myc/DDK-tagged
| Cat.No. : | Fam107a-2909M |
| Product Overview : | Purified recombinant protein of mouse full-length family with sequence similarity 107, member A (Fam107a), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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| Species : | Mouse |
| Source : | HEK293 |
| Tag : | DDK&Myc |
| Description : | Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory. Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development. |
| Molecular Mass : | 17.5 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 μg/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name | Fam107a family with sequence similarity 107, member A [ Mus musculus (house mouse) ] |
| Official Symbol | Fam107a |
| Synonyms | FAM107A; family with sequence similarity 107, member A; protein FAM107A; DRR1; RP24-111B7.1; MGC58343 |
| Gene ID | 268709 |
| mRNA Refseq | NM_183187 |
| Protein Refseq | NP_899010 |
| UniProt ID | Q78TU8 |
Not For Human Consumption!
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