Recombinant Mouse FcRn Protein, His/Avi-tagged

• Cat.No.: FCGRT&B2M-01M
• Product Overview: Mouse FcRn also known as Neonatal Fc receptor is a heterodimer of FCGRT (Fc Fragment of IgG Receptor and Transporter) and B2M (beta 2 microglobulin), GenBank Accession numbers NM_010189 and NM_009735; a.a. 22-297 and a.a. 1-119 respectively. FCGRT has a C-terminal His-Avi-tag. These proteins are co-expressed in a HEK293 expression system.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Avi&His
• Protein Length: 22-297 and a.a. 1-119
• Description: Predicted to enable IgG binding activity and beta-2-microglobulin binding activity. Predicted to be involved in immune response. Predicted to be located in endosome and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in several structures, including genitourinary system; intestine; liver; sensory organ; and skeleton. Orthologous to human FCGRT (Fc fragment of IgG receptor and transporter).
• Form: Aqueous buffer solution
• Molecular Mass: FcRn: 34 kDa; B2M: 14 kDa
• Purity: HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.
• Storage: At least 6 months at –80 centigrade.
• Storage Buffer: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
• Shipping: At -80 centigrade

Gene Information

• Gene Name: Fcgrt Fc fragment of IgG receptor and transporter [ Mus musculus (house mouse) ]
• Official Symbol: Fcgrt
• Synonyms: Fcgrt; Fc fragment of IgG receptor and transporter; FcRn; IgG receptor FcRn large subunit p51; Fc receptor, IgG, alpha chain transporter; igG Fc fragment receptor transporter alpha chain; neonatal Fc receptor
• Gene ID: 14132
• mRNA Refseq: NM_010189
• Protein Refseq: NP_034319
• UniProt ID: Q61559