Recombinant Mouse Gab1 Protein, Myc/DDK-tagged

• Cat.No.: Gab1-3125M
• Product Overview: Purified recombinant protein of mouse full-length growth factor receptor bound protein 2-associated protein 1 (Gab1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 76.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gab1 growth factor receptor bound protein 2-associated protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Gab1
• Synonyms: GAB1; growth factor receptor bound protein 2-associated protein 1; GRB2-associated-binding protein 1; GRB2-associated binder 1; AA408973; AW107238
• Gene ID: 14388
• mRNA Refseq: NM_021356
• Protein Refseq: NP_067331
• UniProt ID: Q9QYY0