Recombinant Mouse Gfral Protein, Gln20-Glu350, N-His-Avi tagged, Biotinylated

• Cat.No.: Gfral-264M
• Product Overview: Recombinant mouse GFRAL/GFR alpha-like-N-His-Avi protein was developed from HEK293 and has a target region of N-His-Avi.

Specification

• Description: Enables glial cell-derived neurotrophic factor receptor activity and receptor tyrosine kinase binding activity. Involved in positive regulation of MAPK cascade and reduction of food intake in response to dietary excess. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of neuron apoptotic process; and stress-activated protein kinase signaling cascade. Located in plasma membrane. Orthologous to human GFRAL (GDNF family receptor alpha like).
• Source: HEK293
• Species: Mouse
• Tag: N-His-Avi
• Protein length: Gln20-Glu350
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM

Gene Information

• Gene Name: Gfral GDNF family receptor alpha like [ Mus musculus ]
• Official Symbol: Gfral
• Synonyms: GFRAL; GDNF family receptor alpha like; GDNF family receptor alpha-like; GDNF receptor alpha-like; Gral; AY457637
• Gene ID: 404194
• mRNA Refseq: NM_205844
• Protein Refseq: NP_995316
• UniProt ID: Q6SJD9