Recombinant Mouse Grk6 Protein, Myc/DDK-tagged
Cat.No. : | Grk6-3312M |
Product Overview : | Purified recombinant protein of mouse full-length G protein-coupled receptor kinase 6 (Grk6), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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- Gene Information
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Description : | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro). |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 67.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Grk6 G protein-coupled receptor kinase 6 [ Mus musculus (house mouse) ] |
Official Symbol : | Grk6 |
Synonyms : | GRK6; G protein-coupled receptor kinase 6; g protein-coupled receptor kinase GRK6; Gprk6 |
Gene ID : | 26385 |
mRNA Refseq : | NM_001112711 |
Protein Refseq : | NP_001106182 |
UniProt ID : | O70293 |
Products Types
◆ Recombinant Protein | ||
GRK6-3938M | Recombinant Mouse GRK6 Protein, His (Fc)-Avi-tagged | +Inquiry |
GRK6-5358H | Recombinant Human GRK6 Protein, GST-tagged | +Inquiry |
GRK6-2360H | Recombinant Human GRK6 Protein, MYC/DDK-tagged | +Inquiry |
GRK6-974H | Active Recombinant Human GRK6 protein(Met1-Arg589), His&GST-tagged | +Inquiry |
GRK6-393H | Recombinant Human GRK6 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GRK6-622HCL | Recombinant Human GRK6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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