Recombinant Mouse Gzmb Protein
Cat.No. : | Gzmb-4520M |
Product Overview : | Mouse Gzmb (PO4187) full length recombinant protein expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016] |
Source : | E. coli |
Species : | Mouse |
Form : | Liquid |
Molecular Mass : | 32 kDa |
Applications : | SDS-PAGE |
Usage : | SDS-PAGE The optimal working dilution should be determined by the end user. |
Storage : | Store at -2 centigrade. For long term storage store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In PBS |
Gene Name : | Gzmb granzyme B [ Mus musculus ] |
Official Symbol : | Gzmb |
Synonyms : | GZMB; granzyme B; granzyme B(G,H); fragmentin-2; cytotoxic cell protease 1; GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1/C11; |
Gene ID : | 14939 |
mRNA Refseq : | NM_013542 |
Protein Refseq : | NP_038570 |
Products Types
◆ Recombinant Protein | ||
Gzmb-273G | Active Recombinant Mouse Gzmb Protein (227 aa) | +Inquiry |
GZMB-2425R | Recombinant Rat GZMB Protein, His (Fc)-Avi-tagged | +Inquiry |
Gzmb-4025M | Recombinant Mouse Gzmb Protein, His (Fc)-Avi-tagged | +Inquiry |
GZMB-3093H | Recombinant Human GZMB Protein, His (Fc)-Avi-tagged | +Inquiry |
Gzmb-070M | Active Recombinant Mouse Gzmb Protein | +Inquiry |
◆ Lysates | ||
GZMB-2944HCL | Recombinant Human GZMB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0404 | GZMB Assay/Inhibitor Screening Fluorometric Kit | +Inquiry |
Kit-0403 | GZMB Activity Fluorometric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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- Reviews
Q&As (5)
Ask a questionGZMB may be used in the development of targeted therapies for viral infections and various immune-related disorders.
GZMB can be used in cancer immunotherapy to target and eliminate cancer cells.
One challenge is to ensure that GZMB selectively targets cancer cells without causing harm to healthy cells.
GZMB-based therapies can be used against various types of cancer, including leukemia, lymphoma, and solid tumors.
GZMB's role in autoimmune diseases is complex. It can contribute to tissue damage in some autoimmune conditions, but its use in treatment is not common.
Customer Reviews (3)
Write a reviewI am delighted to express my complete satisfaction with the quality of GZMB protein, as it precisely suits my experimental requirements.
Their knowledgeable team has been readily available to address any concerns or queries, providing effective solutions and guidance whenever needed.
I have full confidence in the GZMB protein and the exceptional support provided by the manufacturer, making it my top recommendation for researchers seeking a high-quality protein for their experimental needs.
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