Recombinant Mouse Gzmb Protein

• Cat.No.: Gzmb-4520M
• Product Overview: Mouse Gzmb (PO4187) full length recombinant protein expressed in Escherichia coli.

Specification

• Description: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016]
• Source: E. coli
• Species: Mouse
• Form: Liquid
• Molecular Mass: 32 kDa
• Applications: SDS-PAGE
• Usage: SDS-PAGE
  The optimal working dilution should be determined by the end user.
• Storage: Store at -2 centigrade. For long term storage store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In PBS

Gene Information

• Gene Name: Gzmb granzyme B [ Mus musculus ]
• Official Symbol: Gzmb
• Synonyms: GZMB; granzyme B; granzyme B(G,H); fragmentin-2; cytotoxic cell protease 1; GZB; CCP1; Ctla1; Ctla-1; AI553453; CCP-1/C11
• Gene ID: 14939
• mRNA Refseq: NM_013542
• Protein Refseq: NP_038570