Recombinant Mouse Hus1 Protein, MYC/DDK-tagged

• Cat.No.: Hus1-1201M
• Product Overview: Purified recombinant protein of full-length mouse HUS1 checkpoint clamp component (Hus1), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a component of a cell cycle checkpoint complex that causes cell cycle arrest in response to bulky DNA lesions and DNA replication blockage. Together with the proteins Rad9 and Rad1, the encoded protein forms a heterotrimeric complex known as the 9-1-1 complex. Mice lacking the encoded protein develop spontaneous chromosomal abnormalities resulting in embryonic lethality. Alternative splicing of this gene results in multiple transcript variants.
• Molecular Mass: 32.3 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hus1 HUS1 checkpoint clamp component [ Mus musculus (house mouse) ]
• Official Symbol: Hus1
• Synonyms: Hus1; HUS1 checkpoint clamp component; checkpoint protein HUS1; Hus1 homolog
• Gene ID: 15574
• mRNA Refseq: NM_008316
• Protein Refseq: NP_032342
• UniProt ID: Q8BQY8