Recombinant Mouse Icosl Protein, Myc/DDK-tagged

• Cat.No.: Icosl-3470M
• Product Overview: Purified recombinant protein of mouse full-length icos ligand (Icosl), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 36 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Icosl icos ligand [ Mus musculus (house mouse) ]
• Official Symbol: Icosl
• Synonyms: Icosl; icos ligand; L; IC; B7h; GL5; B7RP; GI50; GL50; B7-H2; GL50-; LICOS; B7RP-1; GL50-B; ICOS-L; Icoslg; Ly115l; AU044799; BG071784; mKIAA0653; ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1
• Gene ID: 50723
• mRNA Refseq: NM_015790
• Protein Refseq: NP_056605
• UniProt ID: Q9JHJ8