- Human(26)
- Mouse(4)
- Rhesus Macaque(1)
Recombinant Mouse Il1rap Protein, Myc/DDK-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | Il1rap-3508M Optional Service: Optional requirements on this protein |
Product Overview : | Purified recombinant protein of mouse full-length interleukin 1 receptor accessory protein (Il1rap), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
Description : | Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone; binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand-bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD. May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 41.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Il1rap interleukin 1 receptor accessory protein [ Mus musculus (house mouse) ] |
Official Symbol : | Il1rap |
Synonyms : | IL1RAP; interleukin 1 receptor accessory protein; interleukin-1 receptor accessory protein; IL-1 receptor accessory protein; AI255955; AV239853; IL-1RAcP; 6430709H04Rik |
Gene ID : | 16180 |
mRNA Refseq : | NM_134103 |
Protein Refseq : | NP_598864 |
UniProt ID : | Q61730 |
◆ Recombinant Protein
IL1RAP-356H | Recombinant Human IL1RAP Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Il1rap-444M | Recombinant Mouse IL1RAP Protein, Fc-tagged | +Inquiry |
Il1rap-443M | Recombinant Mouse IL1RAP Protein, His-tagged | +Inquiry |
IL1RAP-1820H | Recombinant Human IL1RAP Protein, MYC/DDK-tagged | +Inquiry |
Il1rap-1576M | Recombinant Mouse Il1rap protein, His & T7-tagged | +Inquiry |
|
◆ Lysates
IL1RAP-2730HCL | Recombinant Human IL1RAP cell lysate | +Inquiry |
|
IL10 IL10RA IL10RB IL11 IL11RA Il11ra1 IL12 IL12A IL12B IL12RB1 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL16 IL17A IL17B Il17c IL17D Il17f IL17RA IL17RD IL18 IL18BP IL18R1 IL18RAP Il19 Il1a Il1b IL1F10 IL1R1 Il1r2 IL1RAP IL1RAPL1 IL1RAPL2 IL1RL1 IL1RL2 Il1rn IL2 Il20 IL20RA IL21 IL21R IL22 IL22BP IL22RA1 IL22RA2 IL23A IL24 Il25 IL27 IL27RA IL28A Il28b IL29 IL2RA IL2RB Il2rg IL3 IL31 IL32 Il33 Il34 IL3RA IL4 IL4R Il4ra Il5 IL5RA Il6 IL6R Il6ra IL6ST Il7 IL7R IL8 IL9 IL36A Il12rb2 IL17RB IL23R IL26 IL31RA IL36B IL36G IL36RN IL37 IL9R IL17RC IL17RE IL28RA IL4I1 IL20RB IL17REL Il11ra2 IL27b IL7RA Il23a&Il12b
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2022 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy