Recombinant Mouse Inpp5k Protein, Myc/DDK-tagged

• Cat.No.: Inpp5k-3550M
• Product Overview: Purified recombinant protein of mouse full-length inositol polyphosphate 5-phosphatase K (Inpp5k), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 54.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Inpp5k inositol polyphosphate 5-phosphatase K [ Mus musculus (house mouse) ]
• Official Symbol: Inpp5k
• Synonyms: INPP5K; inositol polyphosphate 5-phosphatase K; PI-5-phosphatase related; putative PI-5-phosphatase; skeletal muscle and kidney-enriched inositol phosphatase; skeletal muscle and kidney enriched inositol polyphosphate phosphatase; C62; Pps; SKIP
• Gene ID: 19062
• mRNA Refseq: NM_008916
• Protein Refseq: NP_032942
• UniProt ID: Q8C5L6