Recombinant Mouse Interferon Beta 1, Fibroblast

• Cat.No.: Ifnb1-684M
• Product Overview: Recombinant MouseIfnb1 was expressed in E.coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: Non
• Description: Ifnb1 is aprotein that in humans is encoded by the Ifnb1 gene.
• Form: Liquid in PBS,carrier free.
• Molecular Weight: 19.6 kDa
• Concentration: 1 x 106units/ml
• Purity: > 95%
• Endotoxin Level: < 0.1 EU/μg Ifnb1.
• Purification: Combinationof ion exchange, hydrophobic interaction, and size exclusion chromatography.
• Specific Activity: Ifnb1 wastitrated with the use of the cytopathic effect inhibition assay. Units of activitywere measured on mouse L929 cells with encephalomyocarditis virus (EMCV); in thisassay, the EC50 for Ifnb1 is ~ 2.5 U/ml. Theactivity was determined relative to a labstandard of mouse Ifnb1 which was calibrated to the NIH Mouse Ifnb1 standard.
• Storage: Store inworking aliquots at -80°C. Further dilutions should be made in bufferscontainingproteinsuch as 0.1% BSA. Please note that the addition of any carrier proteinintothisproduct may produce unwanted endotoxin. This depends upon the particular applicationemployed. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: Ifnb1

Gene Information

• Gene Name: Ifnb1 interferon beta 1,fibroblast [ Mus musculus ]
• Synonyms: Ifnb1; interferonbeta 1, fibroblast; Ifb; IFNB; IFN-beta; interferon beta; OTTMUSP00000008111
• Gene ID: 15977
• mRNA Refseq: NM_010510
• Protein Refseq: NP_034640
• Chromosome Location: 4 C4; 442.6 cM
• Pathway: Chagas disease(American trypanosomiasis); Cytokine-cytokine receptor interaction; Cytokinesand Inflammatory Response (BioCarta); Cytosolic DNA-sensing pathway;Hepatitis C; Herpes simplex infection; Influenza A; Jak-STAT signalingpathway; Measles; Natural killer cell mediated cytotoxicity; Osteoclast;Osteoclast differentiation; RIG-I-like receptor signaling pathway; Senescenceand Autophagy; Toll-like receptor signaling pathway; Tuberculosis; Type IIinterferon signaling (IFNG)
• Function: cytokine activity;cytokine receptor binding; transcription corepressor activity