Recombinant Mouse L3mbtl2 Protein, Myc/DDK-tagged

• Cat.No.: L3mbtl2-3744M
• Product Overview: Purified recombinant protein of mouse full-length L3MBTL2 polycomb repressive complex 1 subunit (L3mbtl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 79.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: L3mbtl2 L3MBTL2 polycomb repressive complex 1 subunit [ Mus musculus (house mouse) ]
• Official Symbol: L3mbtl2
• Synonyms: L3MBTL2; l(3)mbt-like 2 (Drosophila); lethal(3)malignant brain tumor-like protein 2; l(3)mbt-like protein 2; M4mbt; 4732493N06Rik; MGC31247
• Gene ID: 214669
• mRNA Refseq: NM_145993
• Protein Refseq: NP_666105
• UniProt ID: P59178