Recombinant Mouse Lmbrd1 Protein, Myc/DDK-tagged

• Cat.No.: Lmbrd1-3800M
• Product Overview: Purified recombinant protein of mouse full-length LMBR1 domain containing 1 (Lmbrd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Lysosomal membrane chaperone required to export cobalamin (vitamin B12) from lysosome to the cytosol, allowing its conversion to cofactors. Targets ABCD4 transporter from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal transporter ABCD4 and cytoplasmic MMACHC to transport cobalamin across the lysosomal membrane.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 53.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lmbrd1 LMBR1 domain containing 1 [ Mus musculus (house mouse) ]
• Official Symbol: Lmbrd1
• Synonyms: Lmbrd1; LMBR1 domain containing 1; LMBD1; AV347960; 0910001K20Rik; lysosomal cobalamin transport escort protein LMBD1; LMBR1 domain-containing protein 1; probable lysosomal cobalamin transporter; protein N90b
• Gene ID: 68421
• mRNA Refseq: NM_026719
• Protein Refseq: NP_080995
• UniProt ID: Q8K0B2