Recombinant Mouse Lrrc8c Protein, MYC/DDK-tagged

• Cat.No.: Lrrc8c-162M
• Product Overview: Purified recombinant protein of full-length mouse leucine rich repeat containing 8 family, member C (Lrrc8c), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition. May play a role in adipogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 92.8 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lrrc8c leucine rich repeat containing 8 family, member C [ Mus musculus (house mouse) ]
• Official Symbol: Lrrc8c
• Synonyms: Lrrc8c; leucine rich repeat containing 8 family, member C; AD158; fad158; AI326115; E430036I04Rik; volume-regulated anion channel subunit LRRC8C; factor for adipocyte differentiation 158; leucine-rich repeat-containing protein 8C
• Gene ID: 100604
• mRNA Refseq: NM_133897
• Protein Refseq: NP_598658
• UniProt ID: Q8R502