Recombinant Mouse Macroh2a2 Protein, Myc/DDK-tagged

• Cat.No.: Macroh2a2-3347M
• Product Overview: Purified recombinant protein of mouse full-length H2A histone family, member Y2 (H2afy2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation.
• Molecular Mass: 40.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Macroh2a2 macroH2A.2 histone [ Mus musculus (house mouse) ]
• Official Symbol: Macroh2a2
• Synonyms: Macroh2a2; macroH2A.2 histone; H2afy; H2afy2; core histone macro-H2A.2; H2A histone family, member Y2; histone macroH2A2; mH2A2
• Gene ID: 404634
• mRNA Refseq: NM_207000
• Protein Refseq: NP_996883
• UniProt ID: Q8CCK0