Recombinant Mouse Masp1 Protein, Myc/DDK-tagged

• Cat.No.: Masp1-3966M
• Product Overview: Purified recombinant protein of mouse full-length mannan-binding lectin serine peptidase 1 (Masp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 80.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Masp1 mannan-binding lectin serine peptidase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Masp1
• Synonyms: MASP1; mannan-binding lectin serine peptidase 1; mannan-binding lectin serine protease 1; raRF; MASP-1; serine protease 5; complement factor MASP-3; ra-reactive factor serine protease p100; mannose-binding protein-associated serine protease; mannose-binding lectin-associated serine protease 1; complement-activating component of Ra-reactive factor; CCPII; Crarf; Masp1/3; AW048060
• Gene ID: 17174
• mRNA Refseq: NM_008555
• Protein Refseq: NP_032581
• UniProt ID: P98064