Recombinant Mouse Max Protein, Myc/DDK-tagged

• Cat.No.: Max-3975M
• Product Overview: Purified recombinant protein of mouse full-length Max protein (Max), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. CpG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC:MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 18.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Max Max protein [ Mus musculus (house mouse) ]
• Official Symbol: Max
• Synonyms: MAX; Max protein; protein max; protein myn; myc-associated factor X; myc-binding novel HLH/LZ protein; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; AA960152; AI875693
• Gene ID: 17187
• mRNA Refseq: NM_008558
• Protein Refseq: NP_032584
• UniProt ID: B2RS19