Recombinant Mouse Meaf6 Protein, Myc/DDK-tagged

• Cat.No.: Meaf6-4009M
• Product Overview: Purified recombinant protein of mouse full-length MYST/Esa1-associated factor 6 (Meaf6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 21.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Meaf6 MYST/Esa1-associated factor 6 [ Mus musculus (house mouse) ]
• Official Symbol: Meaf6
• Synonyms: MEAF6; MYST/Esa1-associated factor 6; chromatin modification-related protein MEAF6; protein EAF6 homolog; esa1-associated factor 6 homolog; 2310005N01Rik; 2810036M01Rik
• Gene ID: 70088
• mRNA Refseq: NM_027310
• Protein Refseq: NP_081586
• UniProt ID: Q2VPQ9