Recombinant Mouse Mep1b Protein, His-tagged
| Cat.No. : | Mep1b-7279M |
| Product Overview : | Recombinant Mouse Mep1b Protein with a His tag. |
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| Species : | Mouse |
| Tag : | His |
| Protein Length : | 21-654 |
| Description : | Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components. |
| Form : | Liquid |
| Molecular Mass : | 72.6 kDa |
| AA Sequence : | LPAPEKFVKDIDGGIDQDIFDINQGLGLDLFEGDIKLEANGKNSIIGDHKRWPHTIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWSGEANYISVFKGSGCWSSVGNIHAGKQELSIGTNCDRIATVQHEFLHALGFWHEQSRADRDDYVIIVWDRIQPGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQNGTESTIVTRISEFEDVIGQRMDFSDYDLLKLNQLYNCTSSLSFMDSCDFELENICGMIQSSGDSADWQRVSQVLSGPESDHSKMGQCKDSGFFMHFNTSILNEGATAMLESRLLYPKRGFQCLEFYLYNSGSGNDQLNIYTREYTTGQQGGVLTLQRQIKEVPIGSWQLHYVTLQVTKKFRVVFEGLRGPGTSSGGLSIDDINLSETRCPHHIWHIQNFTQILGGQDTSVYSPPFYSSKGYAFQIYMDLRSSTNVGIYFHLISGANDDQLQWPCPWQQATMTLLDQNPDIRQRMFNQRSITTDPTMTSDNGSYFWDRPSKVGVTDVFPNGTQFSRGIGYGTTVFITRERLKSREFIKGDDIYILLTVEDISHLNSTSAVPDPVPTLAVHNACSEVVCQNGGICVVQDGRAECKCPAGEDWWYMGKRCEKRGSTRDVEHHHHHH |
| Endotoxin : | < 1.0 EU/μg of protein (determined by LAL method) |
| Purity : | > 90 % by SDS-PAGE |
| Stability : | Shelf life: one year from despatch. |
| Storage : | Store undiluted at 2-8 centigrade for one week or (in aliquots) at -20 to -80 centigrade for longer. Avoid repeated freezing and thawing. |
| Concentration : | 0.25 mg/mL (determined by absorbance at 280nm) |
| Storage Buffer : | Phosphate Buffered Saline (pH 7.4) containing 10 % glycerol. |
| Gene Name | Mep1b meprin 1 beta [ Mus musculus (house mouse) ] |
| Official Symbol | Mep1b |
| Synonyms | Mep1b; meprin 1 beta; Mep-1; Mep-1b; meprin A subunit beta; endopeptidase-2; meprin B; meprin beta; EC 3.4.24.63 |
| Gene ID | 17288 |
| mRNA Refseq | NM_008586 |
| Protein Refseq | NP_032612 |
| UniProt ID | Q61847 |
Not For Human Consumption!
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