Recombinant Mouse Mmaa Protein, MYC/DDK-tagged

• Cat.No.: Mmaa-404M
• Product Overview: Purified recombinant protein of full-length mouse methylmalonic aciduria (cobalamin deficiency) type A (Mmaa), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: GTPase, binds and hydrolyzes GTP. Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis. Functions as a G-protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT) and reactivation of the enzyme during catalysis.
• Molecular Mass: 45.9 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mmaa methylmalonic aciduria (cobalamin deficiency) type A [ Mus musculus (house mouse) ]
• Official Symbol: Mmaa
• Synonyms: Mmaa; methylmalonic aciduria (cobalamin deficiency) type A; AI840684; 2810018E08Rik; methylmalonic aciduria type A homolog, mitochondrial
• Gene ID: 109136
• mRNA Refseq: NM_133823
• Protein Refseq: NP_598584
• UniProt ID: Q8C7H1