Recombinant Mouse Mx1 Protein, Myc/DDK-tagged

• Cat.No.: Mx1-4231M
• Product Overview: Purified recombinant protein of mouse full-length MX dynamin-like GTPase 1 (Mx1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the Mx protein family of large GTPases, and functions in the innate immunity system. Interferon alpha/beta treatment or viral infection induces expression of this protein, which subsequently accumulates in the cytoplasm and inhibits viral replication. It has been shown to confer resistance to the influenza virus. This gene produces a functional protein in some feral mouse strains, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a deletion or a nonsense mutation that results in a non-functional gene product.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 72 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mx1 MX dynamin-like GTPase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Mx1
• Synonyms: MX1; myxovirus (influenza virus) resistance 1; interferon-induced GTP-binding protein Mx1; myxoma resistance protein 1; myxovirus (influenza) resistance 1 polypeptide; Mx; Mx-1; AI893580
• Gene ID: 17857
• mRNA Refseq: NM_010846
• Protein Refseq: NP_034976
• UniProt ID: P09922