Recombinant Mouse Mydgf Protein, His-tagged

• Cat.No.: Mydgf-242M
• Product Overview: Recombinant Mouse Mydgf(25-166aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: 25-166aa
• Description: Mydgf, also known as Myeloid-derived growth factor, is a bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and repair after myocardial infarction. It stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Mydgf-deficient mice develop larger infarct scars and more severe contractile dysfunction compared to wild-type mice.
• Form: Liquid. In 20mM Tris-HCl(pH8.0) containing 0.1M NaCl, 10% glycerol
• Molecular Mass: 18.1 kDa (165aa) Confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSVSEPTTV PFDVRPGGVV HSFSQDVGPG NKFTCTFTYA SQGGTNEQWQ MSLGTSEDSQ HFTCTIWRPQ
  GKSYLYFTQF KAELRGAEIE YAMAYSKAAF ERESDVPLKS EEFEVTKTAV SHRPGAFKAE LSKLVIVAKA ARSEL
• Purity: > 95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Mydgf myeloid derived growth factor [ Mus musculus ]
• Official Symbol: Mydgf
• Synonyms: Il25; Ly6elg; D17Wsu104e
• Gene ID: 28106
• mRNA Refseq: NM_080837
• Protein Refseq: NP_543027
• UniProt ID: Q9CPT4