Recombinant Mouse Ndrg1 Protein, Myc/DDK-tagged

• Cat.No.: Ndrg1-4324M
• Product Overview: Purified recombinant protein of mouse full-length N-myc downstream regulated gene 1 (Ndrg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy. Has a role in cell trafficking notably of the Schwann cell and is necessary for the maintenance and development of the peripheral nerve myelin sheath.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 43 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ndrg1 N-myc downstream regulated gene 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ndrg1
• Synonyms: NDRG1; N-myc downstream regulated gene 1; protein NDRG1; protein Ndr1; N-myc downstream regulated 1; N-myc downstream-regulated gene 1 protein; RTP; DRG1; NMSL; Ndr1; Ndrl; TDD5; CAP43; CMT4D; HMSNL; PROXY1
• Gene ID: 17988
• mRNA Refseq: NM_008681
• Protein Refseq: NP_032707
• UniProt ID: Q62433