Recombinant Mouse Nectin2 Protein, Myc/DDK-tagged

• Cat.No.: Nectin2-4357M
• Product Overview: Purified recombinant protein of mouse full-length nectin cell adhesion molecule 2 (Nectin2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 50.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nectin2 nectin cell adhesion molecule 2 [ Mus musculus (house mouse) ]
• Official Symbol: Nectin2
• Synonyms: Nectin2; nectin cell adhesion molecule 2; P; MP; MPH; Pvr; Pvs; Cd112; Pvrl2; necti; AI325026; AI987993; nectin-2; nectin-2; herpes virus entry mediator B; herpesvirus entry mediator B; hveB; mHveB; murine herpes virus entry protein B; murine herpesvirus entry protein B; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity
• Gene ID: 19294
• mRNA Refseq: NM_001159724
• Protein Refseq: NP_001153196
• UniProt ID: P32507