Recombinant Mouse Nes Protein, Myc/DDK-tagged

• Cat.No.: Nes-4377M
• Product Overview: Purified recombinant protein of mouse full-length nestin (Nes), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
• Molecular Mass: 207.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nes nestin [ Mus musculus (house mouse) ]
• Official Symbol: Nes
• Synonyms: NES; nestin; intermediate filament protein; C78523; ESTM46; AA166324
• Gene ID: 18008
• mRNA Refseq: NM_016701
• Protein Refseq: NP_057910
• UniProt ID: Q6P5H2