Recombinant Mouse Numb protein, His & T7-tagged

• Cat.No.: Numb-1739M
• Product Overview: Recombinant Mouse Numb aa. (Leu377~Ser642 (Accession # Q9QZS3)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His&T7
• Protein Length: Leu377~Ser642
• Description: This gene encodes a conserved protein that is distributed asymmetrically during cell division in the developing embryo. The encoded protein participates in cell fate decisions by interacting with the Notch receptor. Loss of function of this gene results in severe defects in neural development and loss of viability. Alternative splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.6kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.1

Gene Information

• Gene Name: Numb numb homolog (Drosophila) [ Mus musculus (house mouse) ]
• Official Symbol: Numb
• Synonyms: Numb; numb homolog (Drosophila); Nb; protein numb homolog; numb gene homolog
• Gene ID: 18222
• mRNA Refseq: NM_001136075.2
• Protein Refseq: NP_001129547.1
• UniProt ID: Q9QZS3