Recombinant Mouse Paox Protein, Myc/DDK-tagged

• Cat.No.: Paox-4672M
• Product Overview: Purified recombinant protein of mouse full-length polyamine oxidase (exo-N4-amino) (Paox), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
• Molecular Mass: 55.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Paox polyamine oxidase (exo-N4-amino) [ Mus musculus (house mouse) ]
• Official Symbol: Paox
• Synonyms: PAOX; polyamine oxidase (exo-N4-amino); peroxisomal N(1)-acetyl-spermine/spermidine oxidase; exo-N4-amino; peroxisomal N1-acetyl-spermine/spermidine oxidase; Pao; AI118225; 2410012F02Rik
• Gene ID: 212503
• mRNA Refseq: NM_153783
• Protein Refseq: NP_722478
• UniProt ID: Q8C0L6