Recombinant Mouse Ppid Protein, Myc/DDK-tagged

• Cat.No.: Ppid-5041M
• Product Overview: Purified recombinant protein of mouse full-length peptidylprolyl isomerase D (cyclophilin D) (Ppid), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity.
• Molecular Mass: 41.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppid peptidylprolyl isomerase D (cyclophilin D) [ Mus musculus (house mouse) ]
• Official Symbol: Ppid
• Synonyms: PPID; peptidylprolyl isomerase D (cyclophilin D); peptidyl-prolyl cis-trans isomerase D; PPIase D; rotamase D; cyclophilin 40; cyclophilin-40; cytoplasmic cyclophilin D; 40 kDa peptidyl-prolyl cis-trans isomerase; Ppif; Ppidl; CYP-40; 4930564J03Rik
• Gene ID: 67738
• mRNA Refseq: NM_026352
• Protein Refseq: NP_080628
• UniProt ID: Q9CR16