Recombinant Mouse Ppp1r1a Protein, Myc/DDK-tagged

• Cat.No.: Ppp1r1a-5068M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 1, regulatory inhibitor subunit 1A (Ppp1r1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 18.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppp1r1a protein phosphatase 1, regulatory inhibitor subunit 1A [ Mus musculus (house mouse) ]
• Official Symbol: Ppp1r1a
• Synonyms: PPP1R1A; protein phosphatase 1, regulatory (inhibitor) subunit 1A; protein phosphatase 1 regulatory subunit 1A; IPP-1; inhibitor-1; protein phosphatase inhibitor 1; protein phosphatase inhibitor-1; I-1; 0610038N18Rik
• Gene ID: 58200
• mRNA Refseq: NM_021391
• Protein Refseq: NP_067366
• UniProt ID: Q9ERT9