Recombinant Mouse Ptprr Protein, Myc/DDK-tagged

• Cat.No.: Ptprr-5251M
• Product Overview: Purified recombinant protein of mouse full-length protein tyrosine phosphatase, receptor type, R (Ptprr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Isoform gamma may have a role in patterning and cellular proliferation of skeletal elements in the precartilaginous/cartilaginous skeleton.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 74.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ptprr protein tyrosine phosphatase, receptor type, R [ Mus musculus (house mouse) ]
• Official Symbol: Ptprr
• Synonyms: PTPRR; protein tyrosine phosphatase, receptor type, R; receptor-type tyrosine-protein phosphatase R; R-PTP-R; STEP-like PTPase; phosphotyrosine phosphatase 13; protein-tyrosine-phosphatase SL; protein-tyrosine-phosphatase-SL; Gmcp1; PTP-SL; PTPBR7; RPTPRR; mPTP213
• Gene ID: 19279
• mRNA Refseq: NM_011217
• Protein Refseq: NP_035347
• UniProt ID: Q62132