Recombinant Mouse Rab14 Protein, Myc/DDK-tagged

• Cat.No.: Rab14-5291M
• Product Overview: Purified recombinant protein of mouse full-length RAB14, member RAS oncogene family (Rab14), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulates, together with its guanine nucleotide exchange factor, DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion. Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 23.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rab14 RAB14, member RAS oncogene family [ Mus musculus (house mouse) ]
• Official Symbol: Rab14
• Synonyms: RAB14; RAB14, member RAS oncogene family; ras-related protein Rab-14; AI314285; AI649155; 0610030G24Rik; 2810475J17Rik; A830021G03Rik; D030017L14Rik
• Gene ID: 68365
• mRNA Refseq: NM_026697
• Protein Refseq: NP_080973
• UniProt ID: Q91V41