Recombinant Mouse Rab3ip Protein, Myc/DDK-tagged

• Cat.No.: Rab3ip-5321M
• Product Overview: Purified recombinant protein of mouse full-length RAB3A interacting protein (Rab3ip), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 47.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rab3ip RAB3A interacting protein [ Mus musculus (house mouse) ]
• Official Symbol: Rab3ip
• Synonyms: RAB3IP; RAB3A interacting protein; rab-3A-interacting protein; rabin-3; gene trap PAT 12; SSX2 interacting protein; SSX2-interacting protein; RAB3A-interacting protein; Rabin3; Gtpat12; B230311A06; MGC90794
• Gene ID: 216363
• mRNA Refseq: NM_001003950
• Protein Refseq: NP_001003950
• UniProt ID: Q68EF0