Recombinant Mouse Ralbp1 Protein, Myc/DDK-tagged

• Cat.No.: Ralbp1-5359M
• Product Overview: Purified recombinant protein of mouse full-length ralA binding protein 1 (Ralbp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 75 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ralbp1 ralA binding protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ralbp1
• Synonyms: RALBP1; ralA binding protein 1; ralA-binding protein 1; DNP-SG ATPase; Ral-interacting protein 1; dinitrophenyl S-glutathione ATPase; Rip1; RLIP76
• Gene ID: 19765
• mRNA Refseq: NM_009067
• Protein Refseq: NP_033093
• UniProt ID: Q62172