Recombinant Mouse Rapgef3 Protein, Myc/DDK-tagged
Cat.No. : | Rapgef3-5377M |
Product Overview : | Purified recombinant protein of mouse full-length Rap guanine nucleotide exchange factor (GEF) 3 (Rapgef3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 99.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Rapgef3 |
Synonyms : | RAPGEF3; Rap guanine nucleotide exchange factor (GEF) 3; rap guanine nucleotide exchange factor 3; cAMP-GEFI; exchange protein directly activated by cAMP 1; cAMP-regulated guanine nucleotide exchange factor I; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; Epac; Epac1; 2310016P22Rik; 9330170P05Rik; MGC19192 |
Gene ID : | 223864 |
mRNA Refseq : | NM_144850 |
Protein Refseq : | NP_659099 |
UniProt ID : | Q8VCC8 |
Products Types
◆ Recombinant Protein | ||
RAPGEF3-4586R | Recombinant Rat RAPGEF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
RAPGEF3-135H | Recombinant Human RAPGEF3, MYC/DDK-tagged | +Inquiry |
RAPGEF3-4927R | Recombinant Rat RAPGEF3 Protein | +Inquiry |
RAPGEF3-3595H | Recombinant Human RAPGEF3 protein, His-tagged | +Inquiry |
RAPGEF3-3056H | Recombinant Human RAPGEF3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
RAPGEF3-2521HCL | Recombinant Human RAPGEF3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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