Recombinant Mouse Rbbp4 Protein, Myc/DDK-tagged

• Cat.No.: Rbbp4-5401M
• Product Overview: Purified recombinant protein of mouse full-length retinoblastoma binding protein 4, chromatin remodeling factor (Rbbp4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 48.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rbbp4 retinoblastoma binding protein 4, chromatin remodeling factor [ Mus musculus (house mouse) ]
• Official Symbol: Rbbp4
• Synonyms: RBBP4; retinoblastoma binding protein 4; histone-binding protein RBBP4; RBBP-4; CAF-I p48; CAF-1 subunit C; CAF-1 p48 subunit; CAF-I 48 kDa subunit; retinoblastoma-binding protein 4; retinoblastoma-binding protein p48; chromatin assembly factor 1 subunit C; chromatin assembly factor I p48 subunit; nucleosome-remodeling factor subunit RBAP48; mRbAp48
• Gene ID: 19646
• mRNA Refseq: NM_009030
• Protein Refseq: NP_033056
• UniProt ID: Q60972