Recombinant Mouse Rbbp7 Protein, Myc/DDK-tagged

• Cat.No.: Rbbp7-5402M
• Product Overview: Purified recombinant protein of mouse full-length retinoblastoma binding protein 7, chromatin remodeling factor (Rbbp7), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
• Molecular Mass: 48.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rbbp7 retinoblastoma binding protein 7, chromatin remodeling factor [ Mus musculus (house mouse) ]
• Official Symbol: Rbbp7
• Synonyms: RBBP7; retinoblastoma binding protein 7; histone-binding protein RBBP7; RBBP-7; retinoblastoma-binding protein 7; retinoblastoma-binding protein p46; histone acetyltransferase type B subunit 2; nucleosome-remodeling factor subunit RBAP46; G1/S transition control protein-binding protein; mRbAp46; AA409861; AI173248; AU019541; BB114024
• Gene ID: 245688
• mRNA Refseq: NM_009031
• Protein Refseq: NP_033057
• UniProt ID: Q60973