Recombinant Mouse Rccd1 Protein, Myc/DDK-tagged

• Cat.No.: Rccd1-5436M
• Product Overview: Purified recombinant protein of mouse full-length RCC1 domain containing 1 (Rccd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 40.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rccd1 RCC1 domain containing 1 [ Mus musculus (house mouse) ]
• Official Symbol: Rccd1
• Synonyms: Rccd1; RCC1 domain containing 1; 5830436H09; E430018M08Rik; RCC1 domain-containing protein 1
• Gene ID: 269955
• mRNA Refseq: NM_173445
• Protein Refseq: NP_775621
• UniProt ID: Q8BTU7