Recombinant Mouse Rfx2 Protein, Myc/DDK-tagged

• Cat.No.: Rfx2-5480M
• Product Overview: Purified recombinant protein of mouse full-length regulatory factor X, 2 (influences HLA class II expression) (Rfx2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 77 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rfx2 regulatory factor X, 2 (influences HLA class II expression) [ Mus musculus (house mouse) ]
• Official Symbol: Rfx2
• Synonyms: RFX2; regulatory factor X, 2 (influences HLA class II expression); DNA-binding protein RFX2; regulatory factor X 2; 5430432H19Rik
• Gene ID: 19725
• mRNA Refseq: NM_009056
• Protein Refseq: NP_033082
• UniProt ID: P48379