Recombinant Mouse Rgs7 Protein, Myc/DDK-tagged

• Cat.No.: Rgs7-5500M
• Product Overview: Purified recombinant protein of mouse full-length regulator of G protein signaling 7 (cDNA clone MGC:58271 IMAGE:6588901), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 55 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rgs7 regulator of G protein signaling 7 [ Mus musculus (house mouse) ]
• Official Symbol: Rgs7
• Synonyms: Rgs7; regulator of G protein signaling 7; regulator of G-protein signaling 7; Regulator of G-protein signaling 7 (RGS7)
• Gene ID: 24012
• mRNA Refseq: NM_011880
• Protein Refseq: NP_036010
• UniProt ID: O54829