Recombinant Mouse Rita1 Protein, MYC/DDK-tagged

• Cat.No.: Rita1-168M
• Product Overview: Purified recombinant protein of full-length mouse RBPJ interacting and tubulin associated 1 (Rita1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 27.1 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rita1 RBPJ interacting and tubulin associated 1 [ Mus musculus (house mouse) ]
• Official Symbol: Rita1
• Synonyms: Rita1; RBPJ interacting and tubulin associated 1; Rita; C86297; AI853657; 1110008J03Rik; RBPJ-interacting and tubulin-associated protein 1
• Gene ID: 100764
• mRNA Refseq: NM_133908
• Protein Refseq: NP_598669
• UniProt ID: Q9D1H0